© 2019 OFRTECH - Process Intensification, Lda 

 

A step forward in process intensification.

Our Company

OFRTECH - Process Intensification, Lda was founded in 2019 as a spin-off company from University of Porto, Portugal, in order to commercialise its patented intellectual property in oscillatory flow reactor (OFR) technology.

 

The company is dedicated to the development and production of oscillatory flow reactors - which can be operating in batch or continuous mode - for mixing intensification of multiphase systems. The R&D of the company is performed in close collaboration with the Laboratory for Process Engineering, Environment, Biotechnology and Energy (LEPABE) - Faculty of Engineering, University of Porto and Centre of Biological Engineering (CEB) - University of Minho.

 

The OFRTECH provide on-site training and on-going technical support.

 

Our Technology

Mixing efficiency is the key factor for the success of several processes. Stirred tank reactor is commonly used at industry, however, problems associated with bad mixing, scale up, product quality and process reproducibility, are typically reported.

In order to overcome these limitations, the OFRTECH commercialize a new generation of oscillatory flow reactor (OFR) based on a patent design.

OFR is basically a column/channel provided with periodic constrictions, called baffles, operating under oscillatory flow mixing (OFM). The liquid or multiphase fluid is typically oscillated in the axial direction by means of diaphragms, bellows or pistons, at one or both ends of the tube/channel, developing an efficient mixing mechanism where fluid moves from the walls to the center of the tube/channel with intensity controlled by the oscillation frequency and amplitude. That mixing mechanism allow a significant increase of heat and mass transfer.  

 
 

Our Products

Oscillatory Flow Plate Unit

photos: Carlos Fernandes

photos: Carlos Fernandes

The technology comprises a unit control and an patented oscillatory flow plate reactor (OFPR). This reactor is based on a modular "LEGO" type system enabling its use in most industrial applications allowing rapid and predictable scale-up without loss of efficiency.

Features:

  • Ready to start;

  • Fully automated​;

  • High chemical durability due to a full metal free system;

  • Can be operated in continuous and batch mode;

  • Outstanding mixing and heat exchange with patented design;

  • Mixing can be improved without changing the solution flow rate (by regulating the frequency and amplitude);

  • Plug flow under laminar flow conditions;

  • Multiple ports allowing extraction for sampling or output;

  • Fully thermostatized;

  • Several ports for probe connectors to suit any PAT​​;

  • Dimensions (mm) (w x d x h): 600 x 700 x 400.

Benefits:

  • Reagent requirements and waste are significantly reduced due to the size, geometry and ability of this novel OFPR to operate at low flow rates;

  • Manufacturing and operating costs are significantly reduced compared to the common reactors;

  • In terms of productivity, excellent heat and mass transfer is obtained;

  • Control of the drop size in liquid/liquid system;

  • Particles can be well suspended up to 50% (w/w);

  • Control of the particle size;

  • Reduction of crystallization time (up to 99%);

  • Up to 35x better on gas-liquid mass transfer (compared to bubble columns;

  • Solids and liquids have similar dispersion coefficients;

  • The OFPR can be assembled and disassembled easily for cleaning and it can even be made of disposable material. 

Commercial Use:

Fine chemical, biochemical, biological and pharmaceutical industries that intend to shift from batch to continuous processes.

Applications:

This novel technology is suitable for multiphase applications such as screening reactions, bioprocess, gas-liquid absorption, liquid-liquid extraction, precipitation and crystallization.

Oscillatory flow plate reactor 

The oscillatory flow plate reactor (OFPR) is suitable for small and medium-scale (millilitres to litres) multiphase applications such as screening reactions, bioprocess, gas-liquid absorption, liquid-liquid extraction, precipitation and crystallization (solids loading up to 50% w/w).

Features:

  • High chemical durability due to a full metal free system;

  • Outstanding mixing and heat exchange with patented design;

  • Low internal volume;

  • Fully thermostatized;

  • Multiple ports allowing extraction for sampling or output;

  • Several ports for probe connectors to suit any PAT;

  • Can be assembled and disassembled easily for cleaning.​

Technical Specifications:

 

Flow rate: up to 200 ml/min;

Temperature: 0°C to 100°C;

Pressure: up to 2 barg;

Materials: PC/PTFE or PC/ETFE/Aluminium (other materials like: Stainless Steel 316L, Hastelloy C22, Peek, etc, on request);

Volume: 113 ml internal volume;

Reactor size: 240 mm x 240 mm or 100 mm x 600 mm (other sizes on request).

 

Contacts

OFRTECH - Process Intensification, Lda​

Sanjotec - Centro Empresarial e Tecnológico 

Rua de Fundões 151, Sala B0.1

3700-121 São João da Madeira, Portugal 

info@ofrtech.com

(+352)256 001 966

  • Black Facebook Icon
  • Black YouTube Icon